Endocrine Abstracts

AimProlactinoma, which is the most important cause of hyperprolactinemia, is an adenoma that originates from lactotropic cells of the pituitary and causes excessive prolactin release. Besides various physiological effects, the immunoregulatory effect of prolactin and its role in the development of autoimmune diseases are well known. The thyroid gland is one of the organs most frequently affected by autoimmunity. However, in our country, there are few stu...

Pituitary apoplexy is a rare and life-threatening disorder often requiring emergency neurosurgical intervention to preserve vision and prevent cerebral herniation syndrome. Infarction or hemorrhage of an enlarged pituitary gland or pituitary tumor is the most common cause of pituitary apoplexy. Early recognition of this disorder is essential for preventing permanent visual loss or death; however, pituitary apoplexy often mimics subarachnoid hemorrhage, which in some cases may ...

BackgroundResistance to thyroid hormone (RTH) involves an altered tissue response to thyroid hormones. RTH is characterized by increased serum thyroid hormone (TH) levels with nonsuppressed serum thyroid-stimulating hormone (TSH) levels. Herein, we report a rare case of RTH with recurrent papillary thyroid carcinoma (PTC).Patient findingsA 38-year-old female patient was admited to outpatient clinic for the ev...

AimNonfunctional adrenal incidentalomas (NFAI’s) are often associated with a high prevalence of insulin resistance (IR). The relationship between IR and thyroid diseases, as well as, thyroid cancer (TC) in patients with NFAI is not yet understood. The aim of this study is to determine the frequency of thyroid disease and TC in NFAI patients and to investigate any possible association of thyroid disease with IR and metabolic disturbances in NFAI pati...

ObjectiveSubacute thyroiditis (SAT) was first described by Fritz De Quervain in 1904 and is generally a self-limiting disease causing pain, fever and temporary hyperthyroidism. It generally develops as a result of postviral inflammatory response following viral upper respiratory tract infections, and it has increased since the covid-19 pandemic in March 2020. We aim to present 2 SAT cases associated with COVID-19.Case Summary<p...

Background and aim: HDR syndrome, is a rare disease characterized with hypoparathyroidism, sensorineural deafness, and renal disease. Patients usually present with hypocalcaemia, tetany, or afebrile convulsions. Hearing loss is usually bilateral. Renal disease includes renal dysplasia, hypoplasia or aplasia. We report a Turkish family of HDR syndrome.Cases: A 56-year-old hypocalcemic deaf male patient and his daughter (25 years) and son (21 years) with h...

Background and aim: Adrenal incidentalomas are discovered incidentally. Incidence has been increasing proportionally to the use of radiographic imaging. We aimed to evaluate patients with adrenal incidentalomas demographically.Subjects and methods: This study was performed between January 2010 and February 2013. Total 320 patients (55.4±11.7 years) with adrenal incidentaloma (86 (26.8%) male (55.2±11.6 years) and 234 (73.1%) female (56.2±1...

Background and aim: Incidence of adrenal incidentaloma is increasing proportionally to the use of radiographic imaging and there were two questions that whether malignant or functional. We aimed to evaluate patients with adrenal incidentalomas in terms of malignancy.Subjects and methods: This study was performed between 2010 and 2013. From 320 patients with adrenal incidentaloma, total 52 patients who underwent surgical intervetion were evaluated. Indica...

Introduction: Adrenocorticalcarcinoma (ACC) is a rare malignancy with an aggressive prognosis, an incidance of 1–2 cases/million/year. It is the cause of 0.2% of all cancer deaths. It is seen in the 4th and 5th decades in adults and mostly unilateral and sporadic. Herein, we present a case of sarcomatoid type ACC which is symptomatic with mass compression and hypertansive attacks.Case presentation: A-52-year-old male was referred to our endocrinolog...

Objective: Hereditary pituitary adenomas (PAs) are rare and occur either isolated or as part of a syndrome. Familial isolated pituitary adenoma (FIPA) is the presence of only PA in at least two members of a family, where “Aryl hydrocarbon receptor interacting protein-AIP” gene mutations have been identified in 10-20% of cases. However, the cause of tumorigenesis in the majority is unknown. We aimed to identify novel genetic variants in a cohort of FIPA patie...